Home Relationships Vagus nerve, GLP-1, and food noise

Vagus nerve, GLP-1, and food noise

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Source: Dingzeyu L / Unsplash

The advent of antiobesity drugs, such as semaglutide, that act on receptors for glucagon-like peptide-1 (GLP-1) provides a pharmacological solution to hunger management. However, the body has its own natural mechanism to regulate hunger via the vagus nerve, offering a sustainable alternative. By optimizing the vagus nerve through lifestyle interventions, we can restore our bodies’ natural ability to regulate hunger and satiety.

The vagus nerve is an important part of the gut-brain axis and serves as the main communication pathway between the gut and the brain. The vagus nerve can sense the metabolites of the microbiota and, through its afferent fibers, ultimately transmits such intestinal information to the complex neural network behind our feeding behavior. Masu.

The health, or reactivity, of our vagus nerve can greatly influence our “food sounds,” or our mental chatter about food and our urge to eat.

understanding food noise

Food noises include persistent mental and physical cues that make you think about food even when you’re not physically hungry. This signal can manifest as cravings, obsessive thoughts about food, or not feeling satisfied after eating. Food sounds are not just a psychological phenomenon. It is deeply rooted in the body’s neurobiological systems, including the vagus nerve.

When the vagus nerve is functioning optimally, it sends accurate signals from the gut to the brain about nutrient intake and energy levels. This communication helps regulate appetite and satiety and reduces unnecessary eating noise. However, when the vagus nerve is damaged, it interferes with the body’s ability to interpret gut signals, leading to increased food noise. As a result, it can be difficult to distinguish true hunger from overeating, impulsive snacking, or emotional or stress-related triggers.

If you find yourself struggling with mealtime noises, know that you’re not alone. Many people struggle with this problem, but it is not a sign of weakness, but rather a sign that your body and mind may be seeking balance. It is essential to approach the fight against food and noise with compassion. Recovery is a journey, and small consistent steps can lead to meaningful change.

how our bodies cope with hunger

In response to the rise in blood sugar levels after a meal, the small intestine releases a hormone called GLP-1. This hormone tells your body that it’s full. Many pharmaceutical companies are now producing drugs that target the GLP-1 pathway to manage hunger. However, our bodies are designed to naturally regulate this process through activation of the vagus nerve.

The vagus nerve contains another pathway to satiety. After eating, afferent neurons in the vagus nerve send information to the brain about fats that have reached the liver, creating a feeling of fullness and suppressing appetite. When your vagus nerve is working effectively, you can feel full within 15 to 20 minutes of starting a meal. Conversely, if you continue to feel hungry after eating, it may indicate vagus nerve dysfunction.

Blood sugar, insulin, vagus nerve

Blood sugar and insulin levels also depend on the vagus nerve. When blood sugar levels rise, the vagus nerve stimulates the pancreas to release insulin. Insulin then signals cells to absorb circulating glucose, a source of energy.

When you’re stressed, your body releases cortisol. Among its many actions, it stimulates the liver to increase glucose production, preparing the body for fight or flight. However, chronic stress can prolong these conditions, keeping blood sugar levels high and repeatedly prompting the pancreas to secrete insulin. Over time, your body can develop insulin resistance and type 2 diabetes.

An optimized vagus nerve ensures proper signal transmission between the gut, brain, and pancreas. Elevated circulating insulin levels caused by insulin resistance cause a hypoglycemic effect that signals hunger, prompting you to consume more carbohydrate-rich foods. This cycle highlights the important role of the vagus nerve in regulating hunger and satiety.

Vagus nerve essentials

Strengthens Vagus Nerve Health

To effectively manage satiety, the vagus nerve must function well. To improve your vagus nerve health, you need to:

Stress Management: Chronic stress reduces vagal tone. Habits like mindfulness, deep breathing, and meditation can reduce stress and increase vagus nerve function. Exercises that condition the vagus nerve: Activities such as singing, gargling, and exposure to cold stimulate the vagus nerve. Reduce inflammation: Inflammation interferes with vagus nerve signaling. An anti-inflammatory diet, adequate sleep, and physical activity can help reduce inflammation.

It’s important to remember that perfection is not the goal. Progress is. If you’re managing stress or binge eating habits, showing yourself kindness and seeking supportive habits can make a big difference. Change is possible and healing is within reach.

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